BiochemistryElsevier Health Sciences, 2013 M06 15 - 812 pages This textbook 'Biochemistry' has become one of the most preferred text books (in India and many other countries) for the students as well as teachers in medical, biological and other allied sciences. The book has undergone three editions, several reprints, and revised reprints in a span of 13 years. There are many biochemistry textbooks in the market. Some of them are purely basic while others are applied, and there are very few books which cover both these aspects together. For this reason, the students learning biochemistry in their undergraduate courses have to depend on multiple books to acquire a sound knowledge of the subject. This book, 'Biochemistry' is unique with a simultaneous and equal emphasis on basic and applied aspects of biochemistry. This textbook offers an integration of medical and pure sciences, comprehensively written to meet the curriculum requirements of undergraduate courses in medical, dental, pharmacy, life-sciences and other categories (agriculture, veterinary, etc.). This book is designed to develop in students a sustained interest and enthusiasm to learn and develop the concepts in biochemistry in a logical and stepwise manner. It incorporates a variety of pedagogic aids, besides colour illustrations to help the students understand the subject quickly and to the maximum. The summary and biomedical/clinical concepts are intended for a rapid absorption and assimilation of the facts and concepts in biochemistry. The self-assessment exercises will stimulate the students to think rather than merely learn the subject. In addition, these exercises (essays, short notes, fill in the blanks, multiple choice questions) set at different difficulty levels, will cater to the needs of all the categories of learners. New to This Edition - The book offers an integration of medical and pure sciences, and is comprehensively written, revised and updated to meet the curriculum requirements of Medical, Pharmacy, Dental, Veterinary, Biotechnology, Agricultural Sciences, Life Sciences, and others studying Biochemistry as one of the subjects. - It is the first text book on Biochemistry in English with multi-colour illustrations by an author from Asia. The use of multicolours is for a clearer understanding of the complicated biochemical reactions. - It is written in a lucid style with the subject being presented as an engaging story growing from elementary information to the most recent advances, and with theoretical discussions being supplemented with illustrations, flowcharts, and tables for easy understanding of Biochemistry. - It has each chapter beginning with a four-line verse followed by the text, biomedical concepts, a summary, and self-assessment exercises. The lively illustrations and text with appropriate headings and sub-headings in bold type faces facilitate reading path clarity and quick recall. - It provides the most recent and essential information on Molecular Biology and Biotechnology, Diabetes, Cancer, Free Radicals, Free radicals and Antioxidants, Prostaglandins, etc. - It describes a wide variety of case studies and biochemical correlations and several newer biomedical aspects- Metabolic syndrome, Therapeutic diets, Atkins diet, Trans fatty acids, Epigenetics, Nutrigenomics, Recombinant ribozymes, Membrane transport disorders, Pleural fluid etc. - It contains the basics (Bioorganic and Biophysical Chemistry, Tools of Biochemistry, Immunology, and Genetics) for beginners to learn easily Biochemistry, origins of biochemical words, confusables in Biochemistry, principles of Practical Biochemistry, and Clinical Biochemistry Laboratory. |
From inside the book
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Page 6
... phospholipids, sterols) and metabolism of drugs, besides supplying Ca2+ for the cellular functions. Golgi apparatus Eukaryotic cells contain a unique cluster of membrane vesicles known as dictyosomes which , in turn , constitute Golgi ...
... phospholipids, sterols) and metabolism of drugs, besides supplying Ca2+ for the cellular functions. Golgi apparatus Eukaryotic cells contain a unique cluster of membrane vesicles known as dictyosomes which , in turn , constitute Golgi ...
Page 23
... – composition, distribution and. Fig . 2.16 : Diagrammatic representation of a proteoglycan complex . Fig . 3.3 : Structures of phospholipids . Chapter 2 : CARBOHYDRATES 23 Hyaluronic acid Chondroitin sulfates Heparin Dermatan sulfate.
... – composition, distribution and. Fig . 2.16 : Diagrammatic representation of a proteoglycan complex . Fig . 3.3 : Structures of phospholipids . Chapter 2 : CARBOHYDRATES 23 Hyaluronic acid Chondroitin sulfates Heparin Dermatan sulfate.
Page 28
... Phospholipids : They contain phosphoric acid and frequently a nitrogenous base . This is in addition to alcohol and fatty acids . (i) Glycerophospholipids : These phospho- lipids contain glycerol as the. 28 Chapter 3 - Lipids ...
... Phospholipids : They contain phosphoric acid and frequently a nitrogenous base . This is in addition to alcohol and fatty acids . (i) Glycerophospholipids : These phospho- lipids contain glycerol as the. 28 Chapter 3 - Lipids ...
Page 29
... (phospholipids and cholesterol). 3. They serve as a source of fat soluble vitamins (A, D, E and K). 4. Lipids are important as cellular metabolic regulators (steroid hormones and prostaglandins). 5. Lipids protect the internal organs ...
... (phospholipids and cholesterol). 3. They serve as a source of fat soluble vitamins (A, D, E and K). 4. Lipids are important as cellular metabolic regulators (steroid hormones and prostaglandins). 5. Lipids protect the internal organs ...
Page 34
... PHOSPHOLIPIDS These are complex or compound lipids containing phosphoric acid , in addition to fatty acids , nitrogenous base and alcohol ( Fig.3.3 ) ... Phospholipids Glycerophospholipids Sphingomyelins Functions of phospholipids.
... PHOSPHOLIPIDS These are complex or compound lipids containing phosphoric acid , in addition to fatty acids , nitrogenous base and alcohol ( Fig.3.3 ) ... Phospholipids Glycerophospholipids Sphingomyelins Functions of phospholipids.
Contents
1 | |
3 | |
9 | |
28 | |
Chapter 4 Proteins and Amino Acids | 43 |
Chapter 5 Nucleic Acids and Nucleotides | 69 |
Chapter 6 Enzymes | 85 |
Chapter 7 Vitamins | 116 |
Chapter 27 Recombinant DNA and Biotechnology | 578 |
Section VI Current Topics | 617 |
Chapter 28 Human Genome Project | 619 |
Chapter 29 Gene Therapy | 625 |
Chapter 30 Bioinformatics | 634 |
Chapter 31 Metabolism of Xenobiotics Detoxification | 638 |
Chapter 32 Prostaglandins and Related Compounds | 644 |
Chapter 33 Biological Membranes and Transport | 650 |
Section II Physiological Biochemistry | 163 |
Chapter 8 Digestion and Absorption | 165 |
Chapter 9 Plasma Proteins | 182 |
Chapter 10 Hemoglobin and Porphyrins | 196 |
Chapter 11 Biological Oxidation | 221 |
Section III Metabolisms | 239 |
Chapter 12 Introduction to Metabolism | 241 |
Chapter 13 Metabolism of Carbohydrates | 244 |
Chapter 14 Metabolism of Lipids | 285 |
Chapter 15 Metabolism of Amino Acids | 330 |
Chapter 16 Integration of Metabolism | 380 |
Chapter 17 Metabolism of Nucleotides | 387 |
Chapter 18 Mineral Metabolism | 403 |
Section IV Clinical Biochemistry and Nutrition | 425 |
Chapter 19 Hormones | 427 |
Chapter 20 Organ Function Tests | 453 |
Chapter 21 Water Electrolyte and Acidbase Balance | 468 |
Chapter 22 Tissue Proteins and Body Fluids | 487 |
Chapter 23 Nutrition | 502 |
Section V Molecular Biology and Biotechnology | 522 |
Chapter 24 DNAŒReplication Recombination and Repair | 523 |
Chapter 25 Transcription and Translation | 542 |
Chapter 26 Regulation of Gene Expression | 566 |
Chapter 34 Free Radicals and Antioxidants | 655 |
Chapter 35 Environmental Biochemistry | 662 |
Chapter 36 Insulin Glucose Homeostasis and Diabetes Mellitus | 669 |
Chapter 37 Cancer | 685 |
Chapter 38 Acquired Immunodeficiency Syndrome AIDS | 695 |
Section VII Basics to Learn Biochemistry | 701 |
Chapter 39 Introduction to Bioorganic Chemistry | 703 |
Chapter 40 Overview of Biophysical Chemistry | 708 |
Chapter 41 Tools of Biochemistry | 719 |
Chapter 42 Immunology | 732 |
Chapter 43 Genetics | 737 |
Section VIII Appendices | 743 |
Answers to Selfassessment Exercises | 745 |
Abbreviations used in this Book | 751 |
Origins of Important Biochemical Words | 756 |
Common Confusables in Biochemistry | 759 |
Practical BiochemistryPrinciples | 763 |
Clinical Biochemistry Laboratory | 769 |
Case Studies with Biochemical Correlations | 772 |
Reference Biochemical Values | 778 |
Index | 779 |
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Common terms and phrases
6-phosphate absorption acetyl CoA activity albumin amino acids anemia Aspartate base bile bilirubin binding biochemical biological biosynthesis blood glucose body bonds cancer carbohydrate carbon catalysed causes cells CH2OH chain cholesterol chromosome citric acid cycle coenzyme complex compounds concentration containing cycle decreased deficiency degradation dehydrogenase diabetes dietary disease disorders energy enzyme eukaryotic excretion factor FADH2 fatty acids formation fructose functions gene genetic genome gluconeogenesis glutamate glycerol glycine glycogen glycolysis heme hemoglobin hormones human increased inhibits insulin intestinal involved ketone bodies kidney kinase lipids lipoproteins liver membrane metabolism mg/dl mitochondria molecular molecules mRNA muscle NAD+ NADH NADPH normal nucleic acids nucleotide organic oxidase oxidation pathway peptide phosphate phospholipids phosphorylation plasma polymerase polypeptide produced proteins purine pyruvate reaction reductase regulation renal sequence serum specific structure substrate synthesis tissues transport triacylglycerols tryptophan tyrosine urea urine vitamin vitamin D