Biochemistry

Front Cover
Elsevier Health Sciences, 2013 M06 15 - 812 pages
This textbook 'Biochemistry' has become one of the most preferred text books (in India and many other countries) for the students as well as teachers in medical, biological and other allied sciences. The book has undergone three editions, several reprints, and revised reprints in a span of 13 years. There are many biochemistry textbooks in the market. Some of them are purely basic while others are applied, and there are very few books which cover both these aspects together. For this reason, the students learning biochemistry in their undergraduate courses have to depend on multiple books to acquire a sound knowledge of the subject. This book, 'Biochemistry' is unique with a simultaneous and equal emphasis on basic and applied aspects of biochemistry. This textbook offers an integration of medical and pure sciences, comprehensively written to meet the curriculum requirements of undergraduate courses in medical, dental, pharmacy, life-sciences and other categories (agriculture, veterinary, etc.). This book is designed to develop in students a sustained interest and enthusiasm to learn and develop the concepts in biochemistry in a logical and stepwise manner. It incorporates a variety of pedagogic aids, besides colour illustrations to help the students understand the subject quickly and to the maximum. The summary and biomedical/clinical concepts are intended for a rapid absorption and assimilation of the facts and concepts in biochemistry. The self-assessment exercises will stimulate the students to think rather than merely learn the subject. In addition, these exercises (essays, short notes, fill in the blanks, multiple choice questions) set at different difficulty levels, will cater to the needs of all the categories of learners. New to This Edition - The book offers an integration of medical and pure sciences, and is comprehensively written, revised and updated to meet the curriculum requirements of Medical, Pharmacy, Dental, Veterinary, Biotechnology, Agricultural Sciences, Life Sciences, and others studying Biochemistry as one of the subjects. - It is the first text book on Biochemistry in English with multi-colour illustrations by an author from Asia. The use of multicolours is for a clearer understanding of the complicated biochemical reactions. - It is written in a lucid style with the subject being presented as an engaging story growing from elementary information to the most recent advances, and with theoretical discussions being supplemented with illustrations, flowcharts, and tables for easy understanding of Biochemistry. - It has each chapter beginning with a four-line verse followed by the text, biomedical concepts, a summary, and self-assessment exercises. The lively illustrations and text with appropriate headings and sub-headings in bold type faces facilitate reading path clarity and quick recall. - It provides the most recent and essential information on Molecular Biology and Biotechnology, Diabetes, Cancer, Free Radicals, Free radicals and Antioxidants, Prostaglandins, etc. - It describes a wide variety of case studies and biochemical correlations and several newer biomedical aspects- Metabolic syndrome, Therapeutic diets, Atkins diet, Trans fatty acids, Epigenetics, Nutrigenomics, Recombinant ribozymes, Membrane transport disorders, Pleural fluid etc. - It contains the basics (Bioorganic and Biophysical Chemistry, Tools of Biochemistry, Immunology, and Genetics) for beginners to learn easily Biochemistry, origins of biochemical words, confusables in Biochemistry, principles of Practical Biochemistry, and Clinical Biochemistry Laboratory.
 

Contents

Section I Chemical Constituents of Life
1
Chapter 1 Biomolecules and the Cell
3
Chapter 2 Carbohydrates
9
Chapter 3 Lipids
28
Chapter 4 Proteins and Amino Acids
43
Chapter 5 Nucleic Acids and Nucleotides
69
Chapter 6 Enzymes
85
Chapter 7 Vitamins
116
Chapter 27 Recombinant DNA and Biotechnology
578
Section VI Current Topics
617
Chapter 28 Human Genome Project
619
Chapter 29 Gene Therapy
625
Chapter 30 Bioinformatics
634
Chapter 31 Metabolism of Xenobiotics Detoxification
638
Chapter 32 Prostaglandins and Related Compounds
644
Chapter 33 Biological Membranes and Transport
650

Section II Physiological Biochemistry
163
Chapter 8 Digestion and Absorption
165
Chapter 9 Plasma Proteins
182
Chapter 10 Hemoglobin and Porphyrins
196
Chapter 11 Biological Oxidation
221
Section III Metabolisms
239
Chapter 12 Introduction to Metabolism
241
Chapter 13 Metabolism of Carbohydrates
244
Chapter 14 Metabolism of Lipids
285
Chapter 15 Metabolism of Amino Acids
330
Chapter 16 Integration of Metabolism
380
Chapter 17 Metabolism of Nucleotides
387
Chapter 18 Mineral Metabolism
403
Section IV Clinical Biochemistry and Nutrition
425
Chapter 19 Hormones
427
Chapter 20 Organ Function Tests
453
Chapter 21 Water Electrolyte and Acidbase Balance
468
Chapter 22 Tissue Proteins and Body Fluids
487
Chapter 23 Nutrition
502
Section V Molecular Biology and Biotechnology
522
Chapter 24 DNAŒReplication Recombination and Repair
523
Chapter 25 Transcription and Translation
542
Chapter 26 Regulation of Gene Expression
566
Chapter 34 Free Radicals and Antioxidants
655
Chapter 35 Environmental Biochemistry
662
Chapter 36 Insulin Glucose Homeostasis and Diabetes Mellitus
669
Chapter 37 Cancer
685
Chapter 38 Acquired Immunodeficiency Syndrome AIDS
695
Section VII Basics to Learn Biochemistry
701
Chapter 39 Introduction to Bioorganic Chemistry
703
Chapter 40 Overview of Biophysical Chemistry
708
Chapter 41 Tools of Biochemistry
719
Chapter 42 Immunology
732
Chapter 43 Genetics
737
Section VIII Appendices
743
Answers to Selfassessment Exercises
745
Abbreviations used in this Book
751
Origins of Important Biochemical Words
756
Common Confusables in Biochemistry
759
Practical BiochemistryPrinciples
763
Clinical Biochemistry Laboratory
769
Case Studies with Biochemical Correlations
772
Reference Biochemical Values
778
Index
779
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About the author (2013)

Over 40 years (30 years as Professor) of teaching experience; authored four other popular books; published about 60 research papers in national and international journals; Gold medallist of Nagpur University; recipient of the Dr Krishnaswamy Best Teacher Award (of Siddhartha medical college); Fellow, National Academy of Clinical Biochemistry, USA, and the Institute of Chemists, India; Member of Research Board of Advisors for the American Biographical Institute; honoured as an Outstanding Scientist Worldwide-2007, by the International Biographical Centre, England.

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